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Does Nerlynx cause hair loss?

Medically reviewed by Carmen Pope, BPharm. Last updated on Aug 14, 2023.

Official answer

by Drugs.com

Hair loss has not been reported as a side effect of Nerlynx. Hair loss is also not an anticipated side effect of Nerlynx because of the targeted way that it works, so if hair loss were to occur, it is probably due to other causes.

The most common side effect of Nerlynx (neratinib) is diarrhea. Other side effects that may be reported include:

  • Dizziness
  • Dry mouth
  • Fainting
  • Increased heart rate
  • Lightheadedness
  • Rapid breathing
  • Sunken eyes
  • Thirst
  • Unusual tiredness or weakness
  • Wrinkled skin.

Some of these side effects may be caused by dehydration due to diarrhea.

For more information, see Nerlynx side effects.

References

Read next

Tucatinib (Tukysa) is used in the treatment of more advanced or metastatic HER2+ breast cancer or HER2+ colorectal cancer, while Neratinib (Nerlynx) is used in the treatment of both early-stage and advanced or metastatic HER2+ breast cancer, but is not approved for use in colorectal cancer. Continue reading

Diarrhea can start as soon as you start taking Nerlynx – 93% of women experienced diarrhea within the first month of treatment (average time to the onset of diarrhea was 8 days) in trials that did not require anti-diarrheal medication to be taken at the same time. However, the risk of diarrhea developing is greatly reduced in those who take loperamide, an antidiarrheal medication, at the same time as Nerlynx. Continue reading

Nerlynx (neratinib) is not a chemo drug it is a type of targeted treatment that works by irreversibly binding to and inhibiting specific receptors on the surface of cancer cells called HER2, HER4, and EGFR receptors, which receive signals that tell cancer to grow and spread. Continue reading

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